Electronic health record company Health IT Services Group plans to open a development center in a former tobacco plant in Durham, N.C. The move will create 45 jobs and take up 12,000 square feet. Health IT Services Group, which recently signed up its 1,000th user, wants to be up and running by November.

The Acumen nEHR electronic health record developed by Brentwood-based Health IT Services Group — a unit of Fresenius Medical Care — recently signed up its 1,000th nephrology provider. The technology platform now is being used in more than 30 states and for almost 2 million patients.